If you have just installed Spybot, you may find that you cannot run a System Scan because the button has been greyed out.
If you are using Windows XP or Vista, and the System Scan button appears as three dots (…), please see here for a solution to this issue.
Spybot’s System Scan button will be accessible when a complete update has been carried out. This is done to ensure that users are scanning their system for all the latest malware and viruses we have on record.
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