Spybot-S&D can appear to hang if the servers are reacting very slowly. This often happens the day new updates are released, when many people try to download them at the same time.
There are a few possible solutions for this problem:
Wait a minute, it should get active again.
Select a different download location: After Search for update, you can select another mirror in the toolbar. To do that, click the small arrow next to the currently selected mirror name.
Please try again later.
Information about updating is also available in a ‘How To’ on this site.