Spybot – Search & Destroy detects registry changes associated with Microsoft Security Center; they are listed as “Windows Security Center”. This is neither a false positive nor a bug. It is just an information about a potential threat – Spybot-S&D only wants to bring to your attention that someone or something disabled one or more notifications in the Windows Security Center, e.g. the notifications that your virus protection is not active or not up-to-date.
If you changed the settings yourself you can safely tell Spybot-S&D to exclude those detections from further scans. In order to do so, please right-click each in turn, then click Exclude this detection from further searches. That way, should any other part of security center settings change, Spybot-S&D will still detect those. The same is true if you have another security solution installed (like McAfee Security Center or Norton Internet Security). These programs disable announcements of Window Security Center in order to signal things by themselves.
The reason why the changes are flagged by Spybot-S&D is that there are also malware programs that disable the notifications so the user does not take note of his security tools not being effective. More information is available in our forum.