There was a problem with compatibility under Windows Vista.
You can solve the problem as follows:
1. Download this new SDUpdate.exe.
To use this beta file, extract the downloaded archive into the main application folder (usually C:\Program Files\Spybot – Search & Destroy\) and replace the old file with the new one.
2. If this does not help go to your SDUpdate.exe file in your program folder:
C:\Program Files\ Spybot – Search & Destroy\
Rightclick the file and choose properties.
Then choose the tab compatibilty.
Activate the checkbox in front of “Run this program in compatibility mode for” and select from the drop down menu “WindowsXP”. Now click “Apply” and “OK”.
That should fix the problem.
This problem has also been discussed in our forum.