Please take a look at the security settings of your firewall (if you are using one) and make sure that Spybot-S&D is not blocked. If it is blocked try un-block it. That should help to get into the updates. If Spybot-S&D is not blocked it is also possible that our server is temporarily not available. Please try again a few hours later.
If this does not help please download the manual updaters from our website. The manual updaters are self-installing, you just need to run them.